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Factors Affecting Anti-retroviral Therapy Adherence Among HIV Positive Children Attending Wollega University Referral Hospital, ART, Nekemte, West Ethiopia, 2019

Received: 8 November 2021    Accepted: 15 December 2021    Published: 24 December 2021
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Abstract

Since the introduction of Antiretroviral Treatments, morbidity and mortality due to HIV/AIDS have been significantly reduced. Through successful prevention of mother-to-child transmission programs, developed countries face few new cases of infant HIV infection annually; however, as a result of successful ART use, children are surviving into adolescence and struggling with many adherence challenges associated with long-term therapy. This study aims to assess factors affecting child antiretroviral treatment adherence at WollegaUniversity Medical Center anti-retroviral therapy clinic. To assess factors that affect child ART adherence among HIV positive children attending Wollega University Referral hospital ART clinic, Nekemte, West Ethiopia, 2019. Cross sectional study design was conducted from March to May/2019 among HIV positive children on ART who have follow-up at Wollega University medical anti-retroviral therapy clinic. Data was collected by interviewing of the care givers of the child using a structured questionnaire. The collected data wascleaned, coded, and analyzed by manual and calculator, and the results found wascompared with findings in the area and aboard, then appropriate conclusions and recommendations wasgiven. Among the 80 study participants, 30 (37.5%) took medications other than ARD. Out of this, 20 (25%) of them took one other tablet per day and the rest were taking two to four other tablets per day. The study showed that the majority (96.3%) of the children had a near perfect (>95%) adherence rate. There were limited researches done in the study area on adherence rate and no research was found describing the national adherence rate.

Published in Biomedical Statistics and Informatics (Volume 6, Issue 4)
DOI 10.11648/j.bsi.20210604.12
Page(s) 76-83
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Adherence, ART, Wollega University Referral Hospital

References
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[2] Havens JF, Mellins CA: Psychiatric aspects of HIV/AIDS. In Rutter’s Child andAdolescent Psychiatry, edn 5. Edited by Rutter M, Bishop D, Pine D, et al. Oxford: Blackwell Publishing; 2018: 945–955.
[3] Yogev R: Balancing the upside and downside of antiretroviral therapy in children. JAMA 20011, 293: 2272–2274.
[4] World Health Organization: Scale up of HIV-related prevention, diagnosis, care, and treatment for infants and children. Available at http://www.who.int/hiv/pub/ paediatric/framework, 2011.
[5] Zhang F, Haberer J, Wei H, et al.: Drug resistance in the Chinese National Pediatric Highly Active Antiretroviral Therapy Cohort: implications for paediatric treatment in the developing world. Int J STD AIDS 2013, 20: 406–409.
[6] Helmut Kloos, YibeltalAssefa, AynalemAdugna, Mesfin Samuel Mulatu, and Damen Haile Mariam, Utilization of antiretroviral treatment in Ethiopia between February and December 2006: spatial, and demographic patterns, Int J Health Geogr.; 6: 45. 2017.
[7] Centers for Disease Control and Prevention: HIV/AIDS Surveillance Report: HIV Infection and AIDS in the United States. Available http://www.cdc.gov/hiv/topics/surveillance/resources/reports/2008report/pdf/2014 SurveillanceReport.pdf.
[8] Wiener L, Mellins CA, Marhefka S, Battles HB: Disclosure ofan HIV diagnosis to children: history, current research, andfuture directions. J DevBehavPediatr 2014, 28: 155–166.
[9] Murphy DA, Belzer M, Durako SJ, et al.: Longitudinalantiretroviral adherence among adolescents infected withhuman immunodeficiency virus. Arch Pediatr Adolesc Med 2010, 159: 764–770. 200 I Behavioral Aspects of HIV Management.
[10] Mellins CA, Brackis-Cott E, Dolezal C, et al.: The role ofpsychosocial and family factors in adherence to antiretroviral treatment in human immunodeficiency virus-infectedchildren. Pediatr Infect Dis J 2012, 23: 1035–1041.
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[13] Nabukeera-Barungi N, Kalyesubula I, Kekitiinwa A, et al.: Adherence to antiretroviral therapy in children attendingMulago Hospital, Kampala. Ann Trop Paediatr 2017, 27: 123–131.
[14] Davies B, Whitsett SF, Bruce A, et al.: A typology of fatigue inchildren with cancer. J PediatrOncolNurs 2012, 19: 12–21.
[15] Ene L, Goetghebuer T, Hainaut M, et al.: Prevalence oflipodystrophy in HIV-infected children: a cross-sectionalstudy. Eur J Pediatr 2017, 166: 13–21.
[16] Adherence to antiretroviral therapy in HIV-infected childrenand adolescents. In Guidelines for the Working Groupon Antiretroviral Therapy and Medical Management ofHIV-Infected Children. Available at http://aidsinfo.nih. gov/Content Files/PediatricGuidelines.pdf. Accessed July 2009.
[17] Feinstein S, Keich R, Becker-Cohen R, et al.: Is noncompliance among adolescent renal transplant recipients inevitable?Pediatrics 2015, 115: 969–973.
[18] Giacomet V, Albano F, Starace F, et al.: Adherence to antiretroviral therapy and its determinants in children with human immunodeficiency virus infection: a multicentre, national study. Act aPaediatr 2013, 92: 1398–1402.
[19] Marhefka SL, VJ, Brown JL, et al.: Caregiver psychosocial characteristics and children’s adherence to antiretroviral therapy. AIDS Patient Care STDS 2011, 20: 429–437.
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  • APA Style

    Edosa Amente Gutema, Gemechu Kejela, Zelalem Keba Babure. (2021). Factors Affecting Anti-retroviral Therapy Adherence Among HIV Positive Children Attending Wollega University Referral Hospital, ART, Nekemte, West Ethiopia, 2019. Biomedical Statistics and Informatics, 6(4), 76-83. https://doi.org/10.11648/j.bsi.20210604.12

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    ACS Style

    Edosa Amente Gutema; Gemechu Kejela; Zelalem Keba Babure. Factors Affecting Anti-retroviral Therapy Adherence Among HIV Positive Children Attending Wollega University Referral Hospital, ART, Nekemte, West Ethiopia, 2019. Biomed. Stat. Inform. 2021, 6(4), 76-83. doi: 10.11648/j.bsi.20210604.12

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    AMA Style

    Edosa Amente Gutema, Gemechu Kejela, Zelalem Keba Babure. Factors Affecting Anti-retroviral Therapy Adherence Among HIV Positive Children Attending Wollega University Referral Hospital, ART, Nekemte, West Ethiopia, 2019. Biomed Stat Inform. 2021;6(4):76-83. doi: 10.11648/j.bsi.20210604.12

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  • @article{10.11648/j.bsi.20210604.12,
      author = {Edosa Amente Gutema and Gemechu Kejela and Zelalem Keba Babure},
      title = {Factors Affecting Anti-retroviral Therapy Adherence Among HIV Positive Children Attending Wollega University Referral Hospital, ART, Nekemte, West Ethiopia, 2019},
      journal = {Biomedical Statistics and Informatics},
      volume = {6},
      number = {4},
      pages = {76-83},
      doi = {10.11648/j.bsi.20210604.12},
      url = {https://doi.org/10.11648/j.bsi.20210604.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.bsi.20210604.12},
      abstract = {Since the introduction of Antiretroviral Treatments, morbidity and mortality due to HIV/AIDS have been significantly reduced. Through successful prevention of mother-to-child transmission programs, developed countries face few new cases of infant HIV infection annually; however, as a result of successful ART use, children are surviving into adolescence and struggling with many adherence challenges associated with long-term therapy. This study aims to assess factors affecting child antiretroviral treatment adherence at WollegaUniversity Medical Center anti-retroviral therapy clinic. To assess factors that affect child ART adherence among HIV positive children attending Wollega University Referral hospital ART clinic, Nekemte, West Ethiopia, 2019. Cross sectional study design was conducted from March to May/2019 among HIV positive children on ART who have follow-up at Wollega University medical anti-retroviral therapy clinic. Data was collected by interviewing of the care givers of the child using a structured questionnaire. The collected data wascleaned, coded, and analyzed by manual and calculator, and the results found wascompared with findings in the area and aboard, then appropriate conclusions and recommendations wasgiven. Among the 80 study participants, 30 (37.5%) took medications other than ARD. Out of this, 20 (25%) of them took one other tablet per day and the rest were taking two to four other tablets per day. The study showed that the majority (96.3%) of the children had a near perfect (>95%) adherence rate. There were limited researches done in the study area on adherence rate and no research was found describing the national adherence rate.},
     year = {2021}
    }
    

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    AB  - Since the introduction of Antiretroviral Treatments, morbidity and mortality due to HIV/AIDS have been significantly reduced. Through successful prevention of mother-to-child transmission programs, developed countries face few new cases of infant HIV infection annually; however, as a result of successful ART use, children are surviving into adolescence and struggling with many adherence challenges associated with long-term therapy. This study aims to assess factors affecting child antiretroviral treatment adherence at WollegaUniversity Medical Center anti-retroviral therapy clinic. To assess factors that affect child ART adherence among HIV positive children attending Wollega University Referral hospital ART clinic, Nekemte, West Ethiopia, 2019. Cross sectional study design was conducted from March to May/2019 among HIV positive children on ART who have follow-up at Wollega University medical anti-retroviral therapy clinic. Data was collected by interviewing of the care givers of the child using a structured questionnaire. The collected data wascleaned, coded, and analyzed by manual and calculator, and the results found wascompared with findings in the area and aboard, then appropriate conclusions and recommendations wasgiven. Among the 80 study participants, 30 (37.5%) took medications other than ARD. Out of this, 20 (25%) of them took one other tablet per day and the rest were taking two to four other tablets per day. The study showed that the majority (96.3%) of the children had a near perfect (>95%) adherence rate. There were limited researches done in the study area on adherence rate and no research was found describing the national adherence rate.
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Author Information
  • Ethiopian Public Health Institute, Addis Ababa. Ethiopia

  • Institute of Public Health, Wollega University, Nekemte, Ethiopia

  • East Wollega Zonal Health Department, Nekemte, Ethiopia

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